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1

Oestrogenic Steroids and Melanoma Cell Interaction with Adjacent Skin Cells Influence Invasion of Melanoma Cells In Vitro

SHEILA MAC NEIL, PAULA EVES, BEN RICHARDSON, RHODA MOLIFE, PAUL LORIGAN, MARK WAGNER, CHRIS LAYTON, RENATO MORANDINI, GHANEM GHANEM

Journal:

Pigment Cell & Melanoma Research

Year:

2000

Language:

english

File:

PDF, 10.01 MB

english, 2000

2

A phase I dose escalation study of the pharmacokinetics and tolerability of ZK 304709, an oral multi-targeted growth inhibitor (MTGI™), in patients with advanced solid tumours

Edwina N. Scott, Anne L. Thomas, L. Rhoda Molife, Samreen Ahmed, Sarah Blagden, Peter C. Fong, Kristin Kowal, Candice McCoy, Herbert Wiesinger, Will Steward, Johann De Bono

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 253 KB

english, 2009

3

FGF Receptor Inhibitors: Role in Cancer Therapy

Gennaro Daniele, Jesus Corral, L. Rhoda Molife, Johann S. de Bono

Journal:

Current Oncology Reports

Year:

2012

Language:

english

File:

PDF, 308 KB

english, 2012

4

A study of the pattern of hospital admissions in a specialist Phase I oncology trials unit: Unplanned admissions as an early indicator of patient attrition

Andre T. Brunetto, Joo Ern Ang, David Olmos, Daniel Tan, Jorge Barriuso, Hendrik-Tobias Arkenau, Timothy A. Yap, L. Rhoda Molife, Udai Banerji, Johann de Bono, Ian Judson, Stan Kaye

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 188 KB

english, 2010

5

Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study

David Olmos, Sophie Postel-Vinay, L Rhoda Molife, Scott H Okuno, Scott M Schuetze, M Luisa Paccagnella, Gretchen N Batzel, Donghua Yin, Kathryn Pritchard-Jones, Ian Judson, Francis P Worden, Antonio G

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 398 KB

english, 2010

6

Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer

Forster, Martin D., Dedes, Konstantin J., Sandhu, Shahneen, Frentzas, Sophia, Kristeleit, Rebecca, Ashworth, Alan, Poole, Christopher J., Weigelt, Britta, Kaye, Stan B., Molife, L. Rhoda

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2011

Language:

english

File:

PDF, 1.21 MB

english, 2011

7

Phase I trials in patients with relapsed, advanced upper gastrointestinal carcinomas: experience in a specialist unit

Khan, Khurum, Ang, Joo Ern, Starling, Naureen, Sclafani, Francesco, Shah, Krunal, Judson, Ian, Molife, L. Rhoda, Banerji, Udai, de Bono, Johann S., Cunningham, David, Kaye, Stan B.

Journal:

Year:

2014

Language:

english

File:

PDF, 250 KB

english, 2014

8

Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors

L Rhoda Molife,Li Yan,Joanna Vitfell-Rasmussen…

Journal:

Journal of Hematology & Oncology

Year:

2014

Language:

english

File:

PDF, 389 KB

english, 2014

9

Phase II, open-label trial to assess QTcF effects, pharmacokinetics and antitumor activity of afatinib in patients with relapsed or refractory solid tumors

Molife, L. Rhoda, Rudman, Sarah M., Alam, Salma, Tan, Daniel S.-W., Kristeleit, Hartmut, Middleton, Gary, Propper, David, Bent, Liz, Stopfer, Peter, Uttenreuther-Fischer, Martina, Wallenstein, Gudrun,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 697 KB

english, 2013

10

Cancer therapeutics: Targeting the apoptotic pathway

Khan, Khurum H., Blanco-Codesido, Montserrat, Molife, L. Rhoda

Journal:

Critical Reviews in Oncology/Hematology

Year:

2014

Language:

english

File:

PDF, 2.75 MB

english, 2014

11

Safety, tolerability and anti-tumour activity of the androgen biosynthesis inhibitor ASP9521 in patients with metastatic castration-resistant prostate cancer: multi-centre phase I/II study

Loriot, Yohann, Fizazi, Karim, Jones, Robert J., Van den Brande, Jan, Molife, Rhoda L., Omlin, Aurelius, James, Nicholas D., Baskin-Bey, Edwina, Heeringa, Marten, Baron, Benoit, Holtkamp, Gertjan M.,

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 1000 KB

english, 2014

12

Targeting the insulin-like growth factor signaling pathway: figitumumab and other novel anticancer strategies

Yap, Timothy A, Olmos, David, Molife, Lulama Rhoda, de Bono, Johann S

Journal:

Expert Opinion on Investigational Drugs

Year:

2011

Language:

english

File:

PDF, 515 KB

english, 2011

13

Targeting the DNA damage response in oncology

Basu, Bristi, Yap, Timothy A., Molife, L. Rhoda, de Bono, Johann S.

Journal:

Current Opinion in Oncology

Year:

2012

Language:

english

File:

PDF, 323 KB

english, 2012

14

Randomized Phase II trial of nintedanib, afatinib and sequential combination in castration-resistant prostate cancer

Molife, L Rhoda, Omlin, Aurelius, Jones, Rob J, Karavasilis, Vasilios, Bloomfield, David, Lumsden, Graeme, Fong, Peter C, Olmos, David, O‘Sullivan, Joe M, Pedley, Ian, Hickish, Tamas, Jenkins, Peter,

Journal:

Future Oncology

Year:

2014

Language:

english

File:

PDF, 2.55 MB

english, 2014

15

Belinostat: clinical applications in solid tumors and lymphoma

Molife, L Rhoda, de Bono, Johann S

Journal:

Expert Opinion on Investigational Drugs

Year:

2011

Language:

english

File:

PDF, 328 KB

english, 2011

16

Targeting cell cycle kinases and kinesins in anticancer drug development

Yap, Timothy A, Molife, L Rhoda, Blagden, Sarah P, de Bono, S

Journal:

Expert Opinion on Drug Discovery

Year:

2007

Language:

english

File:

PDF, 1.85 MB

english, 2007

17

O3.4 * A first-in-human study of intravenous BAL101553, a novel microtubule inhibitor, in patients with advanced solid tumors

Rhoda Molife, L., King, J., Smith, A., D'arcangelo, M., Brown, N., Diamantis, N., Lane, H., Schmitt Hoffmann, A. H., Engelhardt, M., Plummer, R., Kristeleit, R.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 30 KB

english, 2015

18

Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies

Dirix, Luc, Swaisland, Helen, Verheul, Henk M.W., Rottey, Sylvie, Leunen, Karin, Jerusalem, Guy, Rolfo, Christian, Nielsen, Dorte, Molife, L. Rhoda, Kristeleit, Rebecca, Vos-Geelen, Judith de, Mau-Sør

Journal:

Clinical Therapeutics

Year:

2016

Language:

english

File:

PDF, 351 KB

english, 2016

19

A phase I study of intravenous and oral rucaparib in combination with chemotherapy in patients with advanced solid tumours

Wilson, Richard H, Evans, TR Jeffry, Middleton, Mark R, Molife, L Rhoda, Spicer, James, Dieras, Veronique, Roxburgh, Patricia, Giordano, Heidi, Jaw-Tsai, Sarah, Goble, Sandra, Plummer, Ruth

Journal:

British Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 322 KB

english, 2017

20

Clinical factors of response in patients with advanced ovarian cancer participating in early phase clinical trials

George, Angela, Kristeleit, Rebecca, Rafii, Saeed, Michie, Caroline O., Bowen, Rebecca, Michalarea, Vasiliki, van Hagen, Tom, Wong, Mabel, Rallis, Grigorios, Molife, L. Rhoda, Lopez, Juanita, Banerji,

Journal:

European Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 294 KB

english, 2017

21

Pharmacokinetic Effects and Safety of Olaparib Administered with Endocrine Therapy: A Phase I Study in Patients with Advanced Solid Tumours

Plummer, Ruth, Verheul, Henk M., De Vos, Filip Y. F. L., Leunen, Karin, Molife, L. Rhoda, Rolfo, Christian, Grundtvig-Sørensen, Peter, De Grève, Jacques, Rottey, Sylvie, Jerusalem, Guy, Italiano, Anto

Journal:

Advances in Therapy

Year:

2018

Language:

english

File:

PDF, 781 KB

english, 2018

22

Phase 1 dose-finding and pharmacokinetic study of eribulin-liposomal formulation in patients with solid tumours

Evans, T. R. Jeffry, Dean, Emma, Molife, L. Rhoda, Lopez, Juanita, Ranson, Malcolm, El-Khouly, Fatima, Zubairi, Ishtiaq, Savulsky, Claudio, Reyderman, Larisa, Jia, Yan, Sweeting, Lorna, Greystoke, Ala

Journal:

British Journal of Cancer

Year:

2019

File:

PDF, 621 KB

2019

23

Pharmacokinetics and Safety of Olaparib in Patients with Advanced Solid Tumours and Renal Impairment

Rolfo, Christian, de Vos-Geelen, Judith, Isambert, Nicolas, Molife, L. Rhoda, Schellens, Jan H. M., De Grève, Jacques, Dirix, Luc, Grundtvig-Sørensen, Peter, Jerusalem, Guy, Leunen, Karin, Mau-Sørense

Journal:

Clinical Pharmacokinetics

Year:

2019

File:

PDF, 769 KB

2019

24

Pharmacokinetics and safety of olaparib in patients with advanced solid tumours and mild or moderate hepatic impairment

Rolfo, Christian, Isambert, Nicolas, Italiano, Antoine, Molife, L. Rhoda, Schellens, Jan H.M., Blay, Jean-Yves, Decaens, Thomas, Kristeleit, Rebecca, Rosmorduc, Olivier, Demlova, Regina, Lee, Myung-Ah

Journal:

British Journal of Clinical Pharmacology

Year:

2020

Language:

english

File:

PDF, 1.21 MB

english, 2020

25

Phase 1/2a trial of intravenous BAL101553, a novel controller of the spindle assembly checkpoint, in advanced solid tumours

Kristeleit, Rebecca, Evans, Jeffry, Molife, L. Rhoda, Tunariu, Nina, Shaw, Heather, Slater, Sarah, Haris, Noor R. Md, Brown, Nicholas F., Forster, Martin D., Diamantis, Nikolaos, Rulach, Robert, Greys

Journal:

British Journal of Cancer

Year:

2020

File:

PDF, 492 KB

2020